• lovesharon91 posted an update 1 week, 3 days ago

    One limitation of this study is that these results indicate the fluoride levels of specific brands of still bottled water tested at the time of sampling. Further generalizations cannot be applied from these results to the Australian bottled water market in general. Further conclusions may be possible if bottled water manufacturers routinely record (and update) fluoride levels on the labels of still bottled waters. Recognition of the need for the fluoride concentration to be listed on bottled water labels has been identified in the guidelines for the use of fluorides in Australia.3 Better information about fluoride levels in bottled water is of greatest relevance and interest to individuals without buy Alectinib access to a fluoridated reticulated water supply and health professionals. The opportunity to select a particular brand of bottled water on the basis of its fluoride level could have a lasting dental health benefit, if sustained, for these populations. In addition, this information could assist individuals and health professionals to better assess the impact of bottled water consumption on dental health, particularly if it is the primary source of drinking water in unfluoridated areas. This study was funded by the Public Health Branch of the Victorian Department of Health. The authors wish to acknowledge colleagues from other state and territory health departments and Victorian regional colleagues who provided bottled water samples for this study. “”Salivary secretory IgA (sIgA) is said to play an important role in the immune response against dental caries. This study aimed to determine the salivary sIgA levels in healthy smokers and non-smokers, and its correlation with dental caries. A total of 70 healthy subjects were selected and classified into four groups according to dental caries and tobacco smoking habits: smoking with caries (Group 1, n = 15); smoking without caries (Group 2, n = 15); non-smoking with caries (Group 3, n = 15); and non-smoking without caries (Group 4, n = 25). Salivary sIgA was measured using ELISA. The fissure and proximal caries were examined clinically and radiographically. Caries status was determined according to the decay surface index. Smokers showed a higher number of caries and the lowest concentration of sIgA. The highest levels of sIgA were observed in non-smoking and caries-free subjects compared to caries-active smokers (123.2 ± 19.9 vs. 13.3 ± 4.1 μg/ml respectively, p < 0.001). Also, the mean level of sIgA in Group 4 was significantly higher than Group 3 (p = 0.009). More importantly, higher and significant levels of sIgA were found in Group 3 versus Group 1 (p < 0.0001) and Group 2 (p = 0.0004). Our findings indicate that low concentrations of salivary sIgA are correlated with a higher prevalence of dental caries in smokers.